Cultivated Limbal Epithelial Transplantation in Children With Ocular Surface Burns
نویسندگان
چکیده
منابع مشابه
Cultivated limbal epithelial transplantation in children with ocular surface burns.
IMPORTANCE Although several reports are available on the use of conventional and cultured limbal epithelium using various substrates in the treatment of limbal stem cell deficiency (LSCD), the patient populations studied have been largely adults. Thus, to our knowledge, the outcomes of this procedure exclusively in a pediatric population have not been reported previously. OBJECTIVE To report ...
متن کاملLong-term outcome of allogeneic cultivated limbal epithelial transplantation for symblepharon caused by severe ocular burns
BACKGROUND The therapeutic effects of allogeneic cultivated limbal epithelial transplantation (CLET) for symblephara at different degrees caused by ocular burns were evaluated in this study. METHODS A series of interventional cases were involved in this retrospective study. Eighty eyes (80 patients) with symblephara underwent CLET and the success rates of surgical treatment as well as corneal...
متن کاملCultivated limbal stem cell transplantation for ocular surface reconstruction
Severe damage to cell repair mechanisms of the limbal region can lead to many disorders such as vascularized conjunctivalization, keratinization, corneal scarring, and corneal opacification, collectively described as limbal stem cell deficiency (LSCD). Limbal stem cell deficiency may occur as a result of depletion of stem cells or destruction of their stromal niche. In such cases, apart from co...
متن کاملcultivated limbal and oral mucosal epithelial transplantation
stem cells located at the limbus , are the ultimate source for regeneration of the corneal epithelium in the normal and traumatized states. when limbal stem cells are dysfunctional or deficient, limbal stem cell deficiency (lscd) develops. its surgical management depends on laterality and severity of corneal-limbal involvement. conventional methods of stem cell transplantation are conjunctiva...
متن کاملTransplantation of cultivated autologous oral mucosal epithelial cells in patients with severe ocular surface disorders.
BACKGROUND/AIMS To determine outcomes of transplants of cultivated autologous oral epithelial cells in patients with severe ocular surface disorders. METHODS The eyes (n = 6) of four patients with Stevens-Johnson syndrome (three eyes) or chemical burns (three eyes) were studied. Autologous oral epithelial cells, grown for 2-3 weeks on a denuded amniotic membrane carrier in the presence of 3T3...
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ژورنال
عنوان ژورنال: JAMA Ophthalmology
سال: 2013
ISSN: 2168-6165
DOI: 10.1001/jamaophthalmol.2013.2308